Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview
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چکیده
منابع مشابه
Acute traumatic coagulopathy and trauma-induced coagulopathy: an overview
Hemorrhage is the most important contributing factor of acute-phase mortality in trauma patients. Previously, traumatologists and investigators identified iatrogenic and resuscitation-associated causes of coagulopathic bleeding after traumatic injury, including hypothermia, metabolic acidosis, and dilutional coagulopathy that were recognized as primary drivers of bleeding after trauma. However,...
متن کاملAcute Traumatic Coagulopathy: an Endogenous Precursor of Trauma-induced Coagulopathy
Recent findings Trauma causes an acute disruption of the equilibrium between all components of haemostasis (coagulation, anticoagulation, fibrinolysis, platelets and endothelium). In patients with a combination of severe tissue damage and systemic hypoperfusion, this will progress rapidly to an endogenous coagulopathy that is independently associated with worse outcomes. New discoveries of the ...
متن کاملAcute traumatic coagulopathy.
PURPOSE OF REVIEW Recent therapeutic and observational studies have demonstrated improved survival with better management of haemostasis early after injury. This review delineates our current understanding of the clinical importance, aetiology and pathophysiology of acute traumatic coagulopathy (ATC). RECENT FINDINGS Trauma causes an acute disruption of the equilibrium between all components ...
متن کاملAcute traumatic coagulopathy.
PURPOSE OF REVIEW Mortality from trauma remains a global public health challenge, with most preventable deaths due to bleeding. The recognition of acute traumatic coagulopathy as a distinct clinical entity characterized by early coagulation dysfunction, arising prior to medical intervention, has revolutionized trauma management over the last decade. The aim of this article is to review our curr...
متن کاملPathogenesis of acute traumatic coagulopathy.
Acute traumatic coagulopathy (ATC) is an early endogenous process, driven by the combination of tissue injury and shock that is associated with increased mortality and worse outcomes in the polytrauma patient. This review summarizes our current understanding of the pathophysiology of ATC and the role of rapid diagnostics in the management of severe trauma hemorrhage. In particular we consider d...
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ژورنال
عنوان ژورنال: Journal of Intensive Care
سال: 2017
ISSN: 2052-0492
DOI: 10.1186/s40560-016-0196-6